The subsequent major adverse reactions are explained, or explained in bigger detail, in other sections:
Titration and Maintenance of Therapy Separately titrate acetaminophen and codeine phosphate tablets to some dose that gives satisfactory analgesia and minimizes adverse reactions. Constantly reevaluate sufferers obtaining acetaminophen and codeine phosphate tablets to evaluate the upkeep of ache Management, indicators and signs and symptoms of opioid withdrawal, together with other adverse reactions, and also to reassess for the event of dependancy, abuse, or misuse [see Warnings].
are using monoamine oxidase inhibitors (MAOIs) or are actually having them within the previous two weeks. MAOIs, including phenelzine or isocarboxazid, are medicines made use of to deal with depression
Notify people that usage of opioids for an prolonged length of time may perhaps lead to reduced fertility. It's not at all recognised whether these effects on fertility are reversible [see Adverse Response].
The concomitant utilization of acetaminophen and codeine phosphate tablets with all cytochrome P450 3A4 inducers or discontinuation of a cytochrome P450 3A4 inhibitor might end in decreased codeine amounts, higher norcodeine concentrations, and less metabolism by using 2D6 with resultant decrease morphine ranges.
See disposal information at The underside of this part for Instructions regarding how to properly throw away (dispose of) your unused acetaminophen and codeine phosphate tablets.
Zolpidem belongs to a category of prescription drugs named sedative-hypnotics. It really works by slowing activity in the Mind to permit sleep.
Read through all this leaflet meticulously before you start taking this medication mainly because it contains significant info for you personally.
Reserve concomitant prescribing of those medicines for use in individuals for whom substitute treatment alternatives are inadequate. Restrict dosages and durations on the least necessary. Notify clients and caregivers of the likely interaction, educate them within the indicators and indications of respiratory despair (which include sedation).
If concomitant use is warranted, due check here to the fact respiratory depression That could be greater than normally expected and decrease the dosage website of acetaminophen and codeine phosphate tablets and/or perhaps the muscle mass relaxant as necessary.
If a call is built to deal with significant respiratory despair while in the physically dependent affected person, administration from the antagonist really should be begun with treatment and by titration with smaller sized than standard doses on the antagonist.
Speak with your healthcare service provider about naloxone, a medication for the crisis treatment method of an opioid overdose.
Suggest caregivers that acetaminophen and codeine phosphate tablets are contraindicated in all kids more youthful than 12 a long time of age As well as in kids young than 18 decades of age subsequent tonsillectomy and/or adenoidectomy.
Tell your healthcare company for those who develop serious sleepiness or problems breathing, particularly when you start codeine or Once your dose is greater. Get unexpected emergency aid if you have any of the following symptoms.